Glioma vs Glioblastoma

By The Preston Robert Tisch Brain Tumor Center

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When it comes to brain tumors, glioma and glioblastoma are two terms that often surface in medical discussions. These conditions can be confusing, as their names sound remarkably similar, but they have significant differences in terms of prognosis, treatment options, and outcomes. Keep reading as we dive into the world of brain cancer from glioblastoma and gliomas, providing you with a better understanding of these brain tumors.

Glioma vs. Glioblastoma: Exploring the Basics 

What is a Glioma Brain Tumor? 

Glioma is a broad term used to describe tumors that originate in the glial cells of the brain. Glial cells are responsible for supporting and nourishing neurons. Gliomas can vary in severity, ranging from low-grade tumors that grow slowly to high-grade tumors that are aggressive and fast-growing. 

To learn even more about Glioma brain tumors, head to our blog “ What is a Glioma Brain Tumor: Everything You Need to Know”. 

What is a Glioblastoma Brain Tumor? 

Glioblastoma, on the other hand, is a specific type of glioma and is considered the most aggressive and malignant form. It is also known as glioblastoma multiforme. Glioblastoma tumors are highly invasive and tend to infiltrate into nearby brain tissue, making them challenging to treat. 

Differentiating Factors 

To understand the differences between glioma and glioblastoma more clearly, let's examine several key factors.

Location 

  • Glioma: Gliomas can develop in various parts of the brain, including the cerebral hemispheres, brainstem, and spinal cord.
  • Glioblastoma: Glioblastomas are typically found in the cerebral hemispheres of the brain.

Grade

  • Glioma: Gliomas are classified into different grades based on their aggressiveness. Grades range from 1 to 4, with grade 4 being the most aggressive.
  • Glioblastoma: Glioblastoma is always classified as grade 4 due to its highly aggressive nature.

Growth Rate

  • Glioma: The growth rate of gliomas can vary, with some growing slowly over years, while others progress more rapidly.
  • Glioblastoma: Glioblastomas grow rapidly and are known for their aggressive and invasive behavior.

Prognosis 

  • Glioma: The prognosis for gliomas depends on the grade and location. Low-grade gliomas often have a better prognosis than high-grade ones.
  • Glioblastoma: Glioblastoma has a very poor prognosis, with a median survival time of about 15 months, even with treatment.

Treatment Options 

  • Glioma: Treatment options for gliomas include surgery, radiation therapy, and chemotherapy, with the specific approach determined by the tumor's location and grade.
  • Glioblastoma: Treatment for glioblastoma usually involves a combination of surgery, radiation therapy, and chemotherapy. Clinical trials may also be explored.

Symptoms of Glioma and Glioblastoma 

Both gliomas and glioblastomas can produce similar symptoms, including:

  • Headaches
  • Seizures 
  • Cognitive changes 
  • Weakness or numbness in limbs 
  • Nausea and vomiting 
  • Vision problems 

Diagnosing Glioma and Glioblastoma 

Diagnosing these brain tumors typically involves a combination of imaging tests, such as MRI and CT scans, along with a biopsy to confirm the tumor type and grade.

Prognosis and Life Expectancy 

  • Glioma Prognosis: The prognosis for gliomas varies widely depending on factors such as the tumor grade and location. Some patients with low-grade gliomas can survive for many years with appropriate treatment, while high-grade gliomas have a less favorable prognosis.
  • Glioblastoma Prognosis: Glioblastoma has a grim prognosis, with a median survival time of approximately 15 months. Despite aggressive treatment, this type of tumor is highly resistant to therapy.

The Best Brain Tumor Treatment Center 

When it comes to your health, choosing the right treatment center can make all the difference. At the Preston Robert Tisch Brain Tumor Center, we're not just another medical facility; we're pioneers in brain cancer treatment and research. Our team of dedicated doctors is committed to caring for our patients. We offer personalized treatment plans tailored to each patient's specific needs, as well as cutting-edge therapies and advanced surgical techniques designed to provide the best chance at recovery and an improved quality of life. 

Dealing with a brain tumor diagnosis is an emotional journey, and we're here to support you every step of the way. We treat not only the condition but also the person behind it. Committed to making your experience as comfortable and reassuring as possible, we ensure that you and your loved ones feel supported throughout your treatment journey. 

If you're looking for the best brain cancer center near you, your search ends here; our office is conveniently located in Durham, North Carolina. By choosing the Preston Robert Tisch Brain Tumor Center, you're placing your trust in an institution that consistently ranks among the top in the nation. Book a consultation with us today! 

Glioma & Glioblastoma Commonly Asked Questions 

Are glioma and glioblastoma hereditary?

While there is a genetic component to some brain tumors, most gliomas and glioblastomas are not hereditary.

 

Can glioma or glioblastoma be completely cured?

Complete cure is rare, but some patients with low-grade gliomas can achieve long-term remission with treatment.

 

Is radiation therapy always necessary for glioblastoma?

Radiation therapy is a standard part of glioblastoma treatment, but the specific approach may vary depending on individual factors.

 

What are the common side effects of chemotherapy for glioma and glioblastoma?

Common side effects of chemotherapy can include nausea, fatigue, hair loss, and decreased blood cell counts.

 

Can children develop glioma or glioblastoma?

Yes, both children and adults can develop these brain tumors, although the type and prognosis may differ.

 


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