What Is a Glioma Brain Tumor? Everything You Need to Know

By The Preston Robert Tisch Brain Tumor Center

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Gliomas are the most common type of malignant brain tumor in adults, arising from glial cells that support and protect neurons in the brain. These tumors can disrupt brain function and present significant challenges for patients and caregivers. At The Preston Robert Tisch Brain Tumor Center (PRTBTC), we’re here to guide you through the complexities of glioma diagnosis, treatment, and care.

What Is a Glioma?

A glioma is a tumor originating in the central nervous system's glial cells, including the brain and spinal cord. These tumors rarely spread outside the brain but are often challenging to treat due to their tendency to infiltrate healthy brain tissue.

→ Glioma Fast Facts

  • Gliomas can occur at any age but are more common in adults.
  • They account for nearly one-third of all brain tumors.
  • These tumors are categorized by type, grade, and biomarkers.

Types of Gliomas

Gliomas are classified based on the type of glial cells they resemble:

  1. Astrocytomas: Develop from star-shaped glial cells called astrocytes.
  2. Oligodendrogliomas: Originate from cells that insulate neurons and support electrical signaling.
  3. Glioblastomas: Glioblastomas are the most aggressive type of glioma, derived from precursor cells of astrocytes or oligodendrocytes.

Gliomas are also graded based on how quickly they grow:

  • Low-Grade Gliomas (Grades 1-2): Slow-growing and less aggressive.
  • High-Grade Gliomas (Grades 3-4): Rapidly growing and life-threatening.

💡Searching for information about Glioblastoma? Check out our related blog: Glioma vs Glioblastoma.

Symptoms of Gliomas

Gliomas can cause a wide range of symptoms depending on their size and location within the brain. Common symptoms include:

  • Persistent headaches, often worse in the morning.
  • Seizures may be the first noticeable sign.
  • Nausea or vomiting due to increased pressure in the brain.
  • Muscle weakness or difficulty with coordination.
  • Changes in personality, mood, or memory.

If you experience any of these symptoms, consult a healthcare professional promptly.

How Are Gliomas Diagnosed?

Diagnosing a glioma involves a series of steps, including:

  1. Neurological Exam: Assessing coordination, reflexes, and mental function.
  2. Imaging Tests: MRI is the most common tool for identifying gliomas.
  3. Biopsy: A surgical procedure to confirm the type and grade of the tumor.

Treatment Options for Gliomas

Treatment depends on the type, grade, and location of the tumor. Common options include:

  1. Surgery: The primary goal is to remove as much of the tumor as possible while preserving healthy brain tissue.
  2. Radiation Therapy: High-energy rays are used to target and destroy remaining tumor cells.
  3. Chemotherapy: Medications like temozolomide are used to slow or stop tumor growth.
  4. Targeted Therapy: Newer drugs attack specific mutations in glioma cells.
  5. Clinical Trials: Offering access to cutting-edge treatments under investigation.

At The Preston Robert Tisch Brain Tumor Center, our multidisciplinary team collaborates to create personalized treatment plans for each patient. Explore our Adult Neuro-Oncology Program for expert care tailored to adult patients.

Living with a Glioma

While gliomas are challenging to treat, advancements in care are improving outcomes. Many patients live for months or years after diagnosis, especially with a strong support system and expert medical care.

→ Supportive Care at PRTBTC

Our team focuses on improving quality of life through:

  • Symptom management.
  • Emotional and psychological support.
  • Resources for caregivers.

Take the Next Step Toward Glioma Care

At The Preston Robert Tisch Brain Tumor Center, we’re dedicated to guiding patients and their families through every step of their journey with gliomas. Contact us today to schedule a consultation or learn more about our supportive care services.

Schedule an appointment today to learn how we can support your mental health and overall well-being. Our compassionate team of doctors is ready to walk with you every step of the way.

Explore our blog to learn more:

FAQ: Everything You Need to Know About Gliomas

1. Can gliomas be cured?
While most gliomas are not curable, treatments can slow growth, manage symptoms, and improve quality of life.

2. What causes gliomas?
The exact cause is unknown, but gliomas often start with genetic mutations that cause abnormal cell growth.

3. Are gliomas hereditary?
Most gliomas are not inherited and occur due to random genetic changes.

4. Do low-grade gliomas cause epilepsy?
Seizures are a common symptom of low-grade gliomas. Repeated seizures can lead to a clinical diagnosis of epilepsy. Patients with both a glioma and seizures are considered to have tumor-related epilepsy.


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