What Is The Most Common Type of Brain Tumor in Kids?

By The Preston Robert Tisch Brain Tumor Center

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As parents, our children’s health is our utmost concern, and when it comes to brain tumors, knowledge is power. The most prevalent brain tumor affecting children today is what’s known as pilocytic astrocytoma, and by understanding its characteristics, symptoms, and treatment options, we can be better equipped to recognize and address this condition.

Understanding Pilocytic Astrocytoma: The Most Common Brain Tumor in Children

What Is Pilocytic Astrocytoma?

  • Definition: Pilocytic astrocytoma (PA) is a type of brain tumor composed of star-shaped cells called astrocytes, which are star-shaped cells in the brain that support the function of signal-transmitting neurons (nerve cells).
  • Grade and Malignancy: PA is classified by the World Health Organization as a Grade I, nonmalignant tumor. This means that under a microscope, the tumor cells resemble normal (noncancerous) cells and grow slowly. While it doesn’t typically spread to other parts of the body, the tumor itself can become quite large.
  • Commonality: Being the most common brain tumor among children, pilocytic astrocytoma is estimated to affect approximately 1 out of every 100,000 before the age of 20 in the United States(1). 
  • Age Group: Pilocytic astrocytoma impacts roughly 15% of all brain tumor cases among children and approximately 5% of all brain tumors among adults(1).
  • Common Location: The most frequent location the tumor will primarily form is within the cerebellum, situated at the back of the head where the skull meets the neck.

Exploring Childhood Brain Tumors

Brain tumors in children, though less common than in adults, pose significant risks due to their diverse types and brain locations. Recognizing their characteristics is paramount for vigilant health monitoring.

Symptoms and Signs

Recognizing the signs of pediatric brain tumors, such as pilocytic astrocytoma, is crucial for early diagnosis and treatment. Symptoms can vary depending on the tumor's size and location, and any early detection of the symptoms below can greatly improve outcomes for children with brain tumors. 

If your child experiences symptoms spelled out below, seeking medical evaluation and diagnosis is crucial for appropriate management and care.

  • Persistent Headaches 
    • If your child experiences frequent, severe headaches that worsen over time and don't improve with pain medication, it's important to seek medical attention. Additionally, persistent and severe headaches, particularly in the morning, could indicate a brain tumor. These headaches may also be accompanied by nausea and vomiting. Understanding the nature and timeliness of these headaches is crucial for early identification and prompt medical intervention.
  • Fatigue or Lethargy
    • If your child experiences persistent fatigue, especially if it interferes with their daily activities, it could be a sign that their body is coping with the presence of a tumor. While fatigue may result from diverse causes, it's crucial to monitor any unexplained or persistent tiredness and seek medical advice for thorough evaluation and diagnosis.
  • Vomiting
    • Nausea and vomiting, particularly when experienced in the morning or unrelated to meals, can be concerning. These symptoms may indicate increased intracranial pressure, often associated with certain types of brain tumors. 
  • Cognitive and Personality Changes 
    • Mood swings, altered behavior, or personality shifts, along with difficulty in thinking, learning, and concentration, should not be overlooked. These changes may signal underlying neurological challenges, including brain tumors.
  • Vision Disturbances
    • Disturbances in a child’s vision are among the key signs to watch out for. Symptoms may include blurred vision, double vision, or rapid eye movements. If a child experiences unexplained vision loss or notices blurred or double vision, it's important not to ignore these symptoms. Regular eye check-ups become crucial for monitoring visual health, as sometimes children may tilt their heads to compensate for vision changes, which can be noticeable in photographs.
  • Weakness and Coordination Issues 
    • If a child experiences difficulty with arm and leg movements, struggles with walking, or has trouble maintaining balance, it could be a cause for concern. Sudden coordination problems, like difficulty walking in a straight line or climbing stairs, may indicate underlying neurological issues.
  • Seizures 
    • While not common, seizures characterized by uncontrolled movements or convulsions can be a definitive sign of a brain tumor. Recognizing the different types of seizures and their possible association with brain tumors is vital for accurate diagnosis and timely intervention.
  • Growth Changes
    • Changes in growth patterns or puberty occurring suddenly could indicate a brain tumor, as certain hormones are under the brain's regulation.

Causes and Risk Factors

  • Astrocyte Overgrowth: Pilocytic astrocytoma results from an overgrowth of astrocyte cells. However, the exact cause remains uncertain.
  • Possible Factors:
    • Genetic Changes: Some cases may involve genetic alterations, particularly the BRAF gene.
    • Radiation Exposure: Exposure to ionizing radiation during treatment for other cancers (such as leukemia or lymphoma) may contribute.
    • Genetic Conditions: PA can occur in certain genetic conditions, such as Neurofibromatosis Type 1.

Treatment and Prognosis

  • Surgical Removal: The primary treatment for PA is removing the tumor through surgery. Skilled pediatric neurosurgeons will evaluate the tumor’s accessibility and plan its safe removal.
  • Prognosis: Early detection and intervention lead to a favorable prognosis.
  • Long-Term Outlook: Regular follow-up visits and monitoring are essential to ensure the tumor does not recur.
  • Supportive Care: Emotional and psychological support for both the child and family is crucial throughout the treatment journey.

Preventive Measures

When dealing with pediatric brain tumors, preventive measures play a crucial role in early detection and risk reduction. While not all brain tumors are preventable, maintaining regular check-ups and adopting a healthy lifestyle can aid in their timely identification. Encouraging children to embrace a balanced diet, engage in regular exercise, and prioritize hydration are fundamental steps toward promoting overall well-being.

As parents, staying informed empowers us to recognize potential health issues in our children. Pilocytic astrocytoma, though common, is treatable. By familiarizing ourselves with its signs, seeking timely medical attention, and collaborating closely with healthcare professionals, we can ensure the best possible outcome for our little ones. 

Let’s continue advocating for their well-being and spreading awareness about childhood brain tumors. Remember, knowledge serves as our greatest ally in the battle against pediatric brain tumors. Together, let's strive to make a meaningful difference!

Pediatric Brain Tumor Center 

At the Preston Robert Tisch Brain Tumor Center, we are dedicated to offering the highest quality of care for pediatric brain cancer. Whether you've noticed concerning symptoms in your child or have received a diagnosis elsewhere, our specialized team is committed to providing expert and compassionate assistance.

With cutting-edge facilities, access to pediatric clinical trials, and a collaborative approach, we emphasize tailored treatments and comprehensive support for both the child and their family. Your child's well-being is our top priority, and at our pediatric brain tumor center, we encourage you to take proactive steps toward a future filled with healing and optimism. Schedule a consultation today with one of our esteemed pediatric neuro-oncologists specializing in children's brain cancer.

Related Readings

Frequently Asked Questions: Most Common Type of Brain Tumor in Kids

What is Pilocytic Astrocytoma? 

Pilocytic astrocytoma (PA) is a type of brain tumor composed of star-shaped cells called astrocytes. These astrocytes play a crucial role in supporting the function of signal-transmitting neurons (nerve cells) in the brain. PA is classified as a Grade I, nonmalignant tumor by the World Health Organization. This means that, under a microscope, the tumor cells resemble normal (noncancerous) cells and grow slowly. Although PA typically does not spread to other parts of the body, the tumor itself can become quite large.

What are the common signs of pediatric brain tumors?

Common signs include persistent headaches, fatigue or lethargy, vomiting (especially in the morning), cognitive and personality changes, vision disturbances, weakness and coordination issues, seizures, and sudden changes in growth patterns or puberty.

When should I be concerned about my child's headaches?

Seek medical attention if your child experiences frequent, severe headaches that worsen over time and don't improve with pain medication. Persistent and severe headaches, particularly in the morning, could indicate a brain tumor, especially if accompanied by nausea and vomiting.

How can I prevent pediatric brain tumors in my child?

While not all brain tumors are preventable, maintaining regular check-ups and adopting a healthy lifestyle can aid in their timely identification. Encourage your child to embrace a balanced diet, engage in regular exercise, and prioritize hydration to promote overall well-being. Staying informed about common symptoms, such as those of pilocytic astrocytoma, enables early detection and ensures prompt medical attention for the best possible outcome.
 


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